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butabarbital will reduce the extent or impact of nicardipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.butabarbital will lower the level or outcome of carvedilol by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.butabarbital will lower the extent or outcome of alprazolam by affecting hepatic/intes